| New England Patriots at Los Angeles Rams | Thursday, December 10th, 2020 at 8:20pm ET | Bye Week: none |
| Kansas City Chiefs at Miami Dolphins | Sunday, December 13th, 2020 at 1:00pm ET | |
| Houston Texans at Chicago Bears | Sunday, December 13th, 2020 at 1:00pm ET | |
| Tennessee Titans at Jacksonville Jaguars | Sunday, December 13th, 2020 at 1:00pm ET | |
| Denver Broncos at Carolina Panthers | Sunday, December 13th, 2020 at 1:00pm ET | |
| Minnesota Vikings at Tampa Bay Buccaneers | Sunday, December 13th, 2020 at 1:00pm ET | |
| Dallas Cowboys at Cincinnati Bengals | Sunday, December 13th, 2020 at 1:00pm ET | |
| Arizona Cardinals at New York Giants | Sunday, December 13th, 2020 at 1:00pm ET | |
| Indianapolis Colts at Las Vegas Raiders | Sunday, December 13th, 2020 at 4:05pm ET | |
| New York Jets at Seattle Seahawks | Sunday, December 13th, 2020 at 4:05pm ET | |
| Atlanta Falcons at Los Angeles Chargers | Sunday, December 13th, 2020 at 4:25pm ET | |
| Washington Football Team at San Francisco 49ers | Sunday, December 13th, 2020 at 4:25pm ET | |
| New Orleans Saints at Philadelphia Eagles | Sunday, December 13th, 2020 at 4:25pm ET | |
| Green Bay Packers at Detroit Lions | Sunday, December 13th, 2020 at 4:25pm ET | |
| Pittsburgh Steelers at Buffalo Bills | Sunday, December 13th, 2020 at 8:20pm ET | |
| Baltimore Ravens at Cleveland Browns | Monday, December 14th, 2020 at 8:15pm ET |
See the Full Season Schedule
